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SpringerLink电子期刊(3)
Elsevier电子期刊(15)
ACS电子期刊(8)
在“
ACS电子期刊
”中,
命中:
8
条,耗时:小于0.01 秒
在所有数据库中总计命中:
26
条
1.
Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates
作者:
Mihirbaran Mandal
;
Yusheng Wu
;
Jeffrey Misiaszek
;
Guoqing Li
;
Alexei Buevich
;
John P. Caldwell
;
Xiaoxiang Liu
;
Robert D. Mazzola
;
Peter Orth
;
Corey Strickland
;
Johannes Voigt
;
Hongwu Wang
;
Zhaoning Zhu
;
Xia Chen
;
Michael Grzelak
;
Lynn A. Hyde
;
Reshma Kuvelkar
;
Prescott T. Leach
;
Giuseppe Terracina
;
Lili Zhang
;
Qi Zhang
;
Maria S. Michener
;
Brad Smith
;
Kathleen Cox
;
Diane Grotz
;
Leonard Favreau
;
Kaushik Mitra
;
Irina Kazakevich
;
Brian A. McKittrick
;
William Greenlee
;
Matthew E. Kennedy
;
Eric M. Parker
;
Jared
N.
Cumming
;
Andrew W. Stamford
刊名:Journal of Medicinal Chemistry
出版年:2016
2.
Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)–A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer’s Disease
作者:
Jack D. Scott
;
Sarah W. Li
;
Andrew P. J. Brunskill
;
Xia Chen
;
Kathleen Cox
;
Jared
N.
Cumming
;
Mark Forman
;
Eric J. Gilbert
;
Robert A. Hodgson
;
Lynn A. Hyde
;
Qin Jiang
;
Ulrich Iserloh
;
Irina Kazakevich
;
Reshma Kuvelkar
;
Hong Mei
;
John Meredith
;
Jeffrey Misiaszek
;
Peter Orth
;
Lana M. Rossiter
;
Meagan Slater
;
Julie Stone
;
Corey O. Strickland
;
Johannes H. Voigt
;
Ganfeng Wang
;
Hongwu Wang
;
Yusheng Wu
;
William J. Greenlee
;
Eric M. Parker
;
Matthew E. Kennedy
;
Andrew W. Stamford
刊名:Journal of Medicinal Chemistry
出版年:2016
3.
Modeling a Crowdsourced Definition of Molecular Complexity
作者:
Robert P. Sheridan
;
Nicolas Zorn
;
Edward C. Sherer
;
Louis-Charles Campeau
;
Charlie (Zhenyu) Chang
;
Jared
Cumming
;
Matthew L. Maddess
;
Philippe G. Nantermet
;
Christopher J. Sinz
;
Paul D. O鈥橲hea
刊名:Journal of Chemical Information and Modeling
出版年:2014
4.
Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor That Affords Robust CNS A尾 Reduction
作者:
Andrew W. Stamford
;
Jack D. Scott
;
Sarah W. Li
;
Suresh Babu
;
Dawit Tadesse
;
Rachael Hunter
;
Yusheng Wu
;
Jeffrey Misiaszek
;
Jared
N.
Cumming
;
Eric J. Gilbert
;
Chunli Huang
;
Brian A. McKittrick
;
Liwu Hong
;
Tao Guo
;
Zhaoning Zhu
;
Corey Strickland
;
Peter Orth
;
Johannes H. Voigt
;
Matthew E. Kennedy
;
Xia Chen
;
Reshma Kuvelkar
;
Robert Hodgson
;
Lynn A. Hyde
;
Kathleen Cox
;
Leonard Favreau
;
Eric M. Parker
;
William J. Greenlee
刊名:ACS Medicinal Chemistry Letters
出版年:2012
5.
Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation
作者:
Mihirbaran Mandal
;
Zhaoning Zhu
;
Jared
N.
Cumming
;
Xiaoxiang Liu
;
Corey Strickland
;
Robert D. Mazzola
;
John P. Caldwell
;
Prescott Leach
;
Michael Grzelak
;
Lynn Hyde
;
Qi Zhang
;
Giuseppe Terracina
;
Lili Zhang
;
Xia Chen
;
Reshma Kuvelkar
;
Matthew E. Kennedy
;
Leonard Favreau
;
Kathleen Cox
;
Peter Orth
;
Alexei Buevich
;
Johannes Voigt
;
Hongwu Wang
;
Irina Kazakevich
;
Brian A. McKittrick
;
William Greenlee
;
Eric M. Parker
;
Andrew W. Stamford
刊名:Journal of Medicinal Chemistry
出版年:2012
6.
Discovery of Cyclic Acylguanidines as Highly Potent and Selective β-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I—Inhibitor Design and Validation
作者:
Zhaoning Zhu
;
Zhong-Yue Sun
;
Yuanzan Ye
;
Johannes Voigt
;
Corey Strickland
;
Elizabeth M. Smith
;
Jared
Cumming
;
Lingyan Wang
;
Jesse Wong
;
Yu-Sen Wang
;
Daniel F. Wyss
;
Xia Chen
;
Reshma Kuvelkar
;
Matthew
刊名:Journal of Medicinal Chemistry
出版年:2010
7.
Evidence for the Importance of High-Valent Fe=O and of a Diketone in the Molecular Mechanism of Action of Antimalarial Trioxane Analogs of Artemisinin
作者:
Gary H. Posner
;
Sheldon B. Park
;
Lluï
;
sa Gonzá
;
lez
;
Dasong Wang
;
Jared
N.
Cumming
;
Donna Klinedinst
;
Theresa A. Shapiro
;
and Mario D. Bachi
刊名:Journal of the American Chemical Society
出版年:1996
8.
Evidence for Fe(IV):O in the Molecular Mechanism of Action of the Trioxane Antimalarial Artemisinin
作者:
Gary H. Posner
;
Jared
N.
Cumming
;
Poonsakdi Ploypradith
;
and Chang Ho Oh
刊名:Journal of the American Chemical Society
出版年:1995
1
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