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在“ACS电子期刊”中，命中：8条，耗时：小于0.01 秒

1.Discovery and Preclinical Evaluation of BMS-711939, an Oxybenzylglycine Based PPARα Selective Agonist

作者：Yan Shi ; Jun Li ; Lawrence J. Kennedy ; Shiwei Tao ; Andrés S. Hernández ; Zhi Lai ; Sean Chen ; Henry Wong ; Juliang Zhu ; Ashok Trehan ; Ngiap-Kie Lim ; Huiping Zhang ; Bang-Chi Chen ; Kenneth T. Locke ; Kevin M. O’Malley ; Litao Zhang ; Rai Ajit Srivastava ; Bowman Miao ; Daniel S. Meyers ; Hossain Monshizadegan ; Debra Search ; Denise Grimm ; Rongan Zhang ; Thomas Harrity ; Lori K. Kunselman ; Michael Cap ; Jodi Muckelbauer ; Chiehying Chang ; Stanley R. Krystek ; Yi-Xin Li ; Vinayak Hosagrahara ; Lisa Zhang ; Pathanjali Kadiyala ; Carrie Xu ; Michael A. Blanar ; Robert Zahler ; Ranjan Mukherjee ; Peter T. W. Cheng ; Joseph A. Tino

刊名：ACS Medicinal Chemistry Letters

出版年：2016

2.Targeting the BACE1 Active Site Flap Leads to a Potent Inhibitor That Elicits Robust Brain Aβ Reduction in Rodents

作者：Yong-Jin Wu ; Jason Guernon ; Fukang Yang ; Lawrence Snyder ; Jianliang Shi ; Andrea Mcclure ; Ramkumar Rajamani ; Hyunsoo Park ; Alicia Ng ; Hal Lewis ; ChiehYing Chang ; Dan Camac ; Jeremy H. Toyn ; Michael K. Ahlijanian ; Charles F. Albright ; John E. Macor ; Lorin A. Thompson

刊名：ACS Medicinal Chemistry Letters

出版年：2016

3.Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine β-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors

作者：Yong-Jin Wu ; Jason Guernon ; Jianliang Shi ; Lawrence Marcin ; Mendi Higgins ; Ramkumar Rajamani ; Jodi Muckelbauer ; Hal Lewis ; ChiehYing Chang ; Dan Camac ; Jeremy H. Toyn ; Michael K. Ahlijanian ; Charles F. Albright ; John E. Macor ; Lorin A. Thompson

刊名：Journal of Medicinal Chemistry

出版年：2016

4.Small Molecule Reversible Inhibitors of Bruton’s Tyrosine Kinase (BTK): Structure–Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177)

作者：George V. De Lucca ; Qing Shi ; Qingjie Liu ; Douglas G. Batt ; Myra Beaudoin Bertrand ; Rick Rampulla ; Arvind Mathur ; Lorell Discenza ; Celia D’Arienzo ; Jun Dai ; Mary Obermeier ; Rodney Vickery ; Yingru Zhang ; Zheng Yang ; Punit Marathe ; Andrew J. Tebben ; Jodi K. Muckelbauer ; ChiehYing J. Chang ; Huiping Zhang ; Kathleen Gillooly ; Tracy Taylor ; Mark A. Pattoli ; Stacey Skala ; Daniel W. Kukral ; Kim W. McIntyre ; Luisa Salter-Cid ; Aberra Fura ; James R. Burke ; Joel C. Barrish ; Percy H. Carter ; Joseph A. Tino

刊名：Journal of Medicinal Chemistry

出版年：2016

5.Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked

作者：Scott H. Watterson ; George V. De Lucca ; Qing Shi ; Charles M. Langevine ; Qingjie Liu ; Douglas G. Batt ; Myra Beaudoin Bertrand ; Hua Gong ; Jun Dai ; Shiuhang Yip ; Peng Li ; Dawn Sun ; Dauh-Rurng Wu ; Chunlei Wang ; Yingru Zhang ; Sarah C. Traeger ; Mark A. Pattoli ; Stacey Skala ; Lihong Cheng ; Mary T. Obermeier ; Rodney Vickery ; Lorell N. Discenza ; Celia J. D’Arienzo ; Yifan Zhang ; Elizabeth Heimrich ; Kathleen M. Gillooly ; Tracy L. Taylor ; Claudine Pulicicchio ; Kim W. McIntyre ; Michael A. Galella ; Andy J. Tebben ; Jodi K. Muckelbauer ; ChiehYing Chang ; Richard Rampulla ; Arvind Mathur ; Luisa Salter-Cid ; Joel C. Barrish ; Percy H. Carter ; Aberra Fura ; James R. Burke ; Joseph A. Tino

刊名：Journal of Medicinal Chemistry

出版年：2016

6.Image Annotation and Database Mining to Create a Novel Screen for the Chemotype-Dependent Crystallization of HCV NS3 Protease

作者：Herbert E. Klei ; Kevin Kish ; Mark F. Russo ; Steve J. Michalczyk ; Matthew H. Cahn ; Jeffrey Tredup ; ChiehYing Chang ; Javed Khan ; Eric T. Baldwin

刊名：Crystal Growth & Design

出版年：2011

7.Discovery of a 2,4-Disubstituted Pyrrolo[1,2-f][1,2,4]triazine Inhibitor (BMS-754807) of Insulin-like Growth Factor Receptor (IGF-1R) Kinase in Clinical Development

作者：Mark D. Wittman ; Joan M. Carboni ; Zheng Yang ; Francis Y. Lee ; Melissa Antman ; Ricardo Attar ; Praveen Balimane ; Chiehying Chang ; Cliff Chen ; Lorell Discenza ; David Frennesson ; Marco M. Gottardis ; Ann G

刊名：Journal of Medicinal Chemistry

出版年：2009

8.Molecular, Biological, and Preliminary Structural Analysis of Recombinant Bryodin 1, a Ribosome-Inactivating Protein from the Plant Bryonia dioica

作者：Susan L. Gawlak ; Michael Neubauer ; Herbert E. Klei ; ChiehYing Y. Chang ; Howard M. Einspahr ; and Clay B. Siegall

刊名：Biochemistry

出版年：1997

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